Cheapest one-way flights from Detroit to Istanbul in May from $349

Best time to book flights for Detroit (DTW) to Istanbul (IST) flights at AirHint

AirHint found the following cheapest one-way flights from Detroit (DTW) to Istanbul (IST) in May 2025 (see full year).

One-Way flights

12 May Spirit Airlines
10 May Frontier Airlines
04 May Spirit Airlines
30 May Spirit Airlines
23 May Spirit Airlines
05 May Qatar Airways
23 May Turkish Airlines direct
08 May Turkish Airlines direct
12 May Turkish Airlines direct
04 May Turkish Airlines direct

Also check the deals for return flights from Detroit to Istanbul in May.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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