Cheapest one-way flights from Sao Paulo to Madrid in September from $348

Best time to book flights for Sao Paulo (GRU) to Madrid (MAD) flights at AirHint

AirHint found the following cheapest one-way flights from Sao Paulo (GRU) to Madrid (MAD) in September 2025 (see full year).

One-Way flights

22 Sep Air China direct
26 Sep Air China direct
02 Sep Royal Air Maroc
12 Sep Royal Air Maroc
09 Sep Royal Air Maroc
21 Sep Royal Air Maroc
14 Sep Royal Air Maroc
07 Sep Royal Air Maroc
17 Sep Avianca
12 Sep Air China direct

Also check the deals for return flights from Sao Paulo to Madrid in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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