Cheapest one-way flights from Sao Paulo to Santiago in April from $108

Best time to book flights for Sao Paulo (GRU) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest one-way flights from Sao Paulo (GRU) to Santiago (SCL) in April 2025 (see full year).

One-Way flights

19 Apr Sky Airline direct
05 Apr Sky Airline direct
09 Apr Sky Airline direct
21 Apr Sky Airline direct
26 Apr Sky Airline direct
16 Apr Sky Airline direct
27 Apr Sky Airline direct
12 Apr LATAM Airlines Group direct
13 Apr LATAM Airlines Group direct
20 Apr LATAM Airlines Group

Also check the deals for return flights from Sao Paulo to Santiago in April.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Santiago

Cheap car rent in Santiago