Cheapest one-way flights from Guayaquil to Santiago in May from $270

Best time to book flights for Guayaquil (GYE) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest one-way flights from Guayaquil (GYE) to Santiago (SCL) in May 2025 (see full year).

One-Way flights

21 May LATAM Airlines Group
13 May LATAM Airlines Group direct
19 May LATAM Airlines Group direct
20 May LATAM Airlines Group
10 May LATAM Airlines Group
06 May LATAM Airlines Group direct
30 May LATAM Airlines Group
12 May LATAM Airlines Group direct
21 May LATAM Airlines Group direct
05 May LATAM Airlines Group

Also check the deals for return flights from Guayaquil to Santiago in May.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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