Cheapest one-way flights from Houston to Sao Paulo in May from $275

Best time to book flights for Houston (HOU) to Sao Paulo (GRU) flights at AirHint

AirHint found the following cheapest one-way flights from Houston (HOU) to Sao Paulo (GRU) in May 2025 (see full year).

One-Way flights

10 May Spirit Airlines
10 May United direct

Also check the deals for return flights from Houston to Sao Paulo in May.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Sao Paulo

Cheap car rent in Sao Paulo