Cheapest one-way flights from Houston to Panama City in March from $183

Best time to book flights for Houston (HOU) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest one-way flights from Houston (HOU) to Panama City (PTY) in March 2025 (see full year).

One-Way flights

16 Mar Spirit Airlines
12 Mar Frontier Airlines
08 Mar Frontier Airlines
02 Mar Frontier Airlines
04 Mar Spirit Airlines
29 Mar Spirit Airlines
29 Mar United direct
12 Mar United direct
04 Mar United direct
02 Mar United direct

Also check the deals for return flights from Houston to Panama City in March.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Panama City

Cheap car rent in Panama City