Cheapest one-way flights from Los Angeles to Santiago in December from $395

Best time to book flights for Los Angeles (LAX) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest one-way flights from Los Angeles (LAX) to Santiago (SCL) in December 2025 (see full year).

One-Way flights

02 Dec United
30 Dec United
14 Dec WestJet
10 Dec Delta direct
02 Dec Delta direct
30 Dec Delta direct
06 Dec Copa
22 Dec Copa
27 Dec Delta direct
06 Dec Delta direct

Also check the deals for return flights from Los Angeles to Santiago in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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