Cheapest one-way flights from Los Angeles to Santiago in May from $270

Best time to book flights for Los Angeles (LAX) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest one-way flights from Los Angeles (LAX) to Santiago (SCL) in May 2025 (see full year).

One-Way flights

01 May Avianca
22 May Avianca
21 May Avianca
21 May LATAM Airlines Group direct
22 May LATAM Airlines Group direct
26 May Copa
08 May Copa
11 May Copa
20 May Copa
23 May Copa

Also check the deals for return flights from Los Angeles to Santiago in May.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Santiago

Cheap car rent in Santiago