Cheapest one-way flights from Madrid to Istanbul in May from $80

Best time to book flights for Madrid (MAD) to Istanbul (IST) flights at AirHint

AirHint found the following cheapest one-way flights from Madrid (MAD) to Istanbul (IST) in May 2025 (see full year).

One-Way flights

07 May Iberia Express
13 May Iberia Express
29 May Pegasus Airlines direct
21 May Pegasus Airlines direct
27 May Pegasus Airlines direct
14 May Volotea
20 May Wizz Air
16 May Volotea
02 May Wizz Air
03 May Wizz Air

Also check the deals for return flights from Madrid to Istanbul in May.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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