Cheapest one-way flights from Madrid to Prague in December from $58

Best time to book flights for Madrid (MAD) to Prague (PRG) flights at AirHint

AirHint found the following cheapest one-way flights from Madrid (MAD) to Prague (PRG) in December 2025 (see full year).

One-Way flights

21 Dec Ryanair direct
16 Dec Ryanair direct
17 Dec Ryanair direct
18 Dec Ryanair direct
19 Dec Ryanair direct
07 Dec Ryanair direct
10 Dec Iberia
08 Dec Iberia
20 Dec Ryanair direct
02 Dec Iberia Express

Also check the deals for return flights from Madrid to Prague in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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