Cheapest one-way flights from Madrid to Istanbul in September from $109

Best time to book flights for Madrid (MAD) to Istanbul (SAW) flights at AirHint

AirHint found the following cheapest one-way flights from Madrid (MAD) to Istanbul (SAW) in September 2025 (see full year).

One-Way flights

23 Sep Wizz Air Malta
29 Sep Wizz Air Malta
16 Sep easyJet
10 Sep Ryanair
18 Sep easyJet
27 Sep Wizz Air Malta
13 Sep British Airways
25 Sep Ryanair
22 Sep Iberia
20 Sep British Airways

Also check the deals for return flights from Madrid to Istanbul in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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