Cheapest one-way flights from Madrid to Santiago in June from $444

Best time to book flights for Madrid (MAD) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest one-way flights from Madrid (MAD) to Santiago (SCL) in June 2025 (see full year).

One-Way flights

12 Jun Azul Airlines
10 Jun Azul Airlines
15 Jun Azul Airlines
19 Jun Azul Airlines
17 Jun Azul Airlines
05 Jun Ryanair
11 Jun Azul Airlines
02 Jun Ryanair
18 Jun Azul Airlines
13 Jun Azul Airlines

Also check the deals for return flights from Madrid to Santiago in June.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Santiago

Cheap car rent in Santiago