Cheapest one-way flights from Madrid to San Francisco in September from $414
AirHint found the following cheapest one-way flights from Madrid (MAD) to San Francisco (SFO) in September 2025 (see full year).
One-Way flights
| 03 Sep | Ryanair | ||
| 23 Sep | Ryanair | ||
| 02 Sep | Ryanair | ||
| 29 Sep | Vueling Airlines | ||
| 25 Sep | Ryanair | ||
| 20 Sep | Ryanair | ||
| 16 Sep | Ryanair | ||
| 13 Sep | Vueling Airlines | ||
| 27 Sep | Iberia | ||
| 15 Sep | Ryanair |
Also check the deals for return flights from Madrid to San Francisco in September.
The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.
