AirHint found the following cheapest one-way flights from Manchester (MAN) to Istanbul (IST) in May 2026 (see full year).

One-Way flights

05 May	Ryanair
13 May	Ryanair
08 May	Ryanair
20 May	Ryanair
26 May	Ryanair
29 May	Ryanair
08 May	Turkish Airlines	direct
05 May	Turkish Airlines	direct
13 May	Turkish Airlines	direct
26 May	Turkish Airlines	direct

Also check the deals for return flights from Manchester to Istanbul in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Istanbul

Cheap car rent in Istanbul

Cheapest one-way flights from Manchester to Istanbul in May from $144

One-Way flights