Cheapest one-way flights from Orlando to Santo Domingo in September from $215

Best time to book flights for Orlando (MCO) to Santo Domingo (SDQ) flights at AirHint

AirHint found the following cheapest one-way flights from Orlando (MCO) to Santo Domingo (SDQ) in September 2025 (see full year).

One-Way flights

05 Sep United
05 Sep jetBlue direct
08 Sep Copa
04 Sep Copa

Also check the deals for return flights from Orlando to Santo Domingo in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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