Cheapest one-way flights from Chicago to Madrid in April from $359

Best time to book flights for Chicago (MDW) to Madrid (MAD) flights at AirHint

AirHint found the following cheapest one-way flights from Chicago (MDW) to Madrid (MAD) in April 2025 (see full year).

One-Way flights

09 Apr Frontier Airlines
05 Apr Frontier Airlines
10 Apr Frontier Airlines
06 Apr Frontier Airlines
11 Apr Frontier Airlines
03 Apr Frontier Airlines
04 Apr Frontier Airlines
29 Apr Air France
21 Apr Delta
27 Apr Air France

Also check the deals for return flights from Chicago to Madrid in April.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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