Cheapest one-way flights from Melbourne to Santiago in December from $1242

Best time to book flights for Melbourne (MEL) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest one-way flights from Melbourne (MEL) to Santiago (SCL) in December 2025 (see full year).

One-Way flights

29 Dec LATAM Airlines Group
03 Dec Qatar Airways
25 Dec LATAM Airlines Group direct
30 Dec LATAM Airlines Group direct
26 Dec LATAM Airlines Group
04 Dec Qatar Airways
06 Dec Qatar Airways
09 Dec Qatar Airways
05 Dec Qatar Airways
23 Dec LATAM Airlines Group direct

Also check the deals for return flights from Melbourne to Santiago in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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