Cheapest one-way flights from Melbourne to Santiago in December from $629

Best time to book flights for Melbourne (MEL) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest one-way flights from Melbourne (MEL) to Santiago (SCL) in December 2025 (see full year).

One-Way flights

30 Dec LATAM Airlines Group direct
25 Dec LATAM Airlines Group direct
27 Dec LATAM Airlines Group direct
23 Dec Jetstar
23 Dec LATAM Airlines Group direct
24 Dec LATAM Airlines Group
16 Dec LATAM Airlines Group direct
09 Dec LATAM Airlines Group direct
13 Dec LATAM Airlines Group direct
06 Dec LATAM Airlines Group direct

Also check the deals for return flights from Melbourne to Santiago in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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