Cheapest one-way flights from Mexico City to Madrid in October from $374

Best time to book flights for Mexico City (MEX) to Madrid (MAD) flights at AirHint

AirHint found the following cheapest one-way flights from Mexico City (MEX) to Madrid (MAD) in October 2025 (see full year).

One-Way flights

27 Oct Iberia direct
22 Oct Iberia direct
12 Oct Iberia direct
15 Oct Iberia direct
06 Oct Iberia direct
08 Oct Iberia direct
13 Oct Iberia direct
14 Oct Iberia direct
19 Oct Iberia direct
05 Oct Iberia direct

Also check the deals for return flights from Mexico City to Madrid in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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