Cheapest one-way flights from Mexico City to Santo Domingo in September from $149

Best time to book flights for Mexico City (MEX) to Santo Domingo (SDQ) flights at AirHint

AirHint found the following cheapest one-way flights from Mexico City (MEX) to Santo Domingo (SDQ) in September 2025 (see full year).

One-Way flights

03 Sep Arajet direct
29 Sep Arajet direct

Also check the deals for return flights from Mexico City to Santo Domingo in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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