Cheapest one-way flights from New York to Santiago in September from $356

Best time to book flights for New York (NYC) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest one-way flights from New York (NYC) to Santiago (SCL) in September 2025 (see full year).

One-Way flights

26 Sep Avianca
26 Sep LATAM Airlines Group direct

Also check the deals for return flights from New York to Santiago in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Santiago

Cheap car rent in Santiago