Cheapest one-way flights from Chicago to Rome in April from $295

Best time to book flights for Chicago (ORD) to Rome (FCO) flights at AirHint

AirHint found the following cheapest one-way flights from Chicago (ORD) to Rome (FCO) in April 2025 (see full year).

One-Way flights

01 Apr Frontier Airlines
29 Apr Spirit Airlines
27 Apr Spirit Airlines
14 Apr WestJet
01 Apr Iberia direct
08 Apr American Airlines direct
26 Apr Air Serbia
11 Apr TAP
24 Apr Turkish Airlines
29 Apr Iberia direct

Also check the deals for return flights from Chicago to Rome in April.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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