Cheapest one-way flights from Prague to Madrid in May from $56

Best time to book flights for Prague (PRG) to Madrid (MAD) flights at AirHint

AirHint found the following cheapest one-way flights from Prague (PRG) to Madrid (MAD) in May 2025 (see full year).

One-Way flights

10 May Ryanair direct
06 May easyJet
08 May Ryanair direct
07 May Ryanair direct
15 May Ryanair direct
05 May Wizz Air Malta
24 May Ryanair direct
31 May Ryanair direct
29 May Ryanair direct
13 May Ryanair direct

Also check the deals for return flights from Prague to Madrid in May.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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