Cheapest one-way flights from Panama City to Madrid in August from $497

Best time to book flights for Panama City (PTY) to Madrid (MAD) flights at AirHint

AirHint found the following cheapest one-way flights from Panama City (PTY) to Madrid (MAD) in August 2025 (see full year).

One-Way flights

13 Aug Avianca
04 Aug Avianca
15 Aug Avianca
19 Aug Avianca
23 Aug Avianca
31 Aug Avianca
17 Aug Avianca
04 Aug Air Europa direct
30 Aug Avianca
23 Aug Air Europa direct

Also check the deals for return flights from Panama City to Madrid in August.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Madrid

Cheap car rent in Madrid