Cheapest one-way flights from Panama City to Santiago in April from $292

Best time to book flights for Panama City (PTY) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest one-way flights from Panama City (PTY) to Santiago (SCL) in April 2025 (see full year).

One-Way flights

20 Apr Avianca
05 Apr Avianca
23 Apr Avianca
25 Apr Avianca
16 Apr Avianca
17 Apr Avianca
25 Apr Copa direct
16 Apr Copa direct
17 Apr Copa direct
05 Apr Copa direct

Also check the deals for return flights from Panama City to Santiago in April.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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