Cheapest one-way flights from Rome to Prague in September from $25

Best time to book flights for Rome (ROM) to Prague (PRG) flights at AirHint

AirHint found the following cheapest one-way flights from Rome (ROM) to Prague (PRG) in September 2025 (see full year).

One-Way flights

17 Sep Ryanair direct
15 Sep Wizz Air Malta direct
02 Sep Wizz Air Malta direct
10 Sep Wizz Air Malta direct
06 Sep Wizz Air Malta direct
24 Sep Wizz Air Malta direct
16 Sep Wizz Air Malta direct
04 Sep Wizz Air Malta direct
03 Sep Wizz Air Malta direct
11 Sep Wizz Air Malta direct

Also check the deals for return flights from Rome to Prague in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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