Cheapest one-way flights from Rome to Prague in September from $33

Best time to book flights for Rome (ROM) to Prague (PRG) flights at AirHint

AirHint found the following cheapest one-way flights from Rome (ROM) to Prague (PRG) in September 2025 (see full year).

One-Way flights

19 Sep Wizz Air Malta direct
12 Sep Wizz Air Malta direct
03 Sep Wizz Air Malta direct
06 Sep Wizz Air Malta direct
24 Sep Wizz Air Malta direct
23 Sep Wizz Air Malta direct
27 Sep Wizz Air Malta direct
17 Sep Wizz Air Malta direct
11 Sep Ryanair direct
22 Sep Wizz Air Malta direct

Also check the deals for return flights from Rome to Prague in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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