Cheapest one-way flights from Rome to Santiago in September from $443

Best time to book flights for Rome (ROM) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest one-way flights from Rome (ROM) to Santiago (SCL) in September 2025 (see full year).

One-Way flights

17 Sep LEVEL
05 Sep LEVEL
22 Sep LEVEL
20 Sep Turkish Airlines

Also check the deals for return flights from Rome to Santiago in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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