Cheapest one-way flights from Santiago to Madrid in October from $643
AirHint found the following cheapest one-way flights from Santiago (SCL) to Madrid (MAD) in October 2025 (see full year).
One-Way flights
| 16 Oct | Turkish Airlines | ||
| 16 Oct | Iberia | direct | |
| 31 Oct | Iberia | direct |
Also check the deals for return flights from Santiago to Madrid in October.
The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.
