Cheapest one-way flights from Santo Domingo to Madrid in April from $456

Best time to book flights for Santo Domingo (SDQ) to Madrid (MAD) flights at AirHint

AirHint found the following cheapest one-way flights from Santo Domingo (SDQ) to Madrid (MAD) in April 2025 (see full year).

One-Way flights

06 Apr Frontier Airlines
24 Apr Frontier Airlines
04 Apr Copa
28 Apr Frontier Airlines
07 Apr Sky High Aviation Services
29 Apr Arajet
30 Apr jetBlue
25 Apr Frontier Airlines
10 Apr Copa
08 Apr Frontier Airlines

Also check the deals for return flights from Santo Domingo to Madrid in April.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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