Cheapest one-way flights from Santo Domingo to Madrid in May from $449

Best time to book flights for Santo Domingo (SDQ) to Madrid (MAD) flights at AirHint

AirHint found the following cheapest one-way flights from Santo Domingo (SDQ) to Madrid (MAD) in May 2025 (see full year).

One-Way flights

04 May jetBlue
06 May Arajet
03 May Frontier Airlines
10 May Spirit Airlines
05 May Frontier Airlines
14 May Spirit Airlines
08 May Frontier Airlines
09 May Spirit Airlines
13 May Arajet
26 May Iberia direct

Also check the deals for return flights from Santo Domingo to Madrid in May.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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