Cheapest one-way flights from Santo Domingo to Madrid in September from $422

Best time to book flights for Santo Domingo (SDQ) to Madrid (MAD) flights at AirHint

AirHint found the following cheapest one-way flights from Santo Domingo (SDQ) to Madrid (MAD) in September 2025 (see full year).

One-Way flights

30 Sep Arajet
29 Sep Arajet
26 Sep Arajet
11 Sep Arajet
04 Sep Arajet
07 Sep Arajet
08 Sep Arajet
16 Sep Arajet
22 Sep Iberia direct
02 Sep Arajet

Also check the deals for return flights from Santo Domingo to Madrid in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Madrid

Cheap car rent in Madrid