Cheapest one-way flights from Santo Domingo to Santiago in October from $354

Best time to book flights for Santo Domingo (SDQ) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest one-way flights from Santo Domingo (SDQ) to Santiago (SCL) in October 2025 (see full year).

One-Way flights

21 Oct Copa
13 Oct Copa
12 Oct Copa
01 Oct Copa

Also check the deals for return flights from Santo Domingo to Santiago in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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