Cheapest one-way flights from San Francisco to Rome in April from $245

Best time to book flights for San Francisco (SFO) to Rome (FCO) flights at AirHint

AirHint found the following cheapest one-way flights from San Francisco (SFO) to Rome (FCO) in April 2025 (see full year).

One-Way flights

19 Apr Frontier Airlines
26 Apr Frontier Airlines
15 Apr Frontier Airlines
18 Apr Alaska Airlines
12 Apr Frontier Airlines
27 Apr Frontier Airlines
17 Apr Frontier Airlines
11 Apr Frontier Airlines
10 Apr Frontier Airlines
09 Apr Scandinavian Airlines

Also check the deals for return flights from San Francisco to Rome in April.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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