Cheapest one-way flights from San Francisco to Rome in April from $275

Best time to book flights for San Francisco (SFO) to Rome (FCO) flights at AirHint

AirHint found the following cheapest one-way flights from San Francisco (SFO) to Rome (FCO) in April 2025 (see full year).

One-Way flights

08 Apr Frontier Airlines
21 Apr Alaska Airlines
17 Apr Frontier Airlines
16 Apr Frontier Airlines
13 Apr Alaska Airlines
14 Apr Alaska Airlines
07 Apr Alaska Airlines
05 Apr Frontier Airlines
20 Apr Frontier Airlines
02 Apr Brussels Airlines

Also check the deals for return flights from San Francisco to Rome in April.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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