Cheapest one-way flights from San Francisco to Rome in May from $309

Best time to book flights for San Francisco (SFO) to Rome (FCO) flights at AirHint

AirHint found the following cheapest one-way flights from San Francisco (SFO) to Rome (FCO) in May 2025 (see full year).

One-Way flights

13 May Frontier Airlines
12 May Frontier Airlines
11 May Frontier Airlines
06 May Frontier Airlines
14 May Alaska Airlines
05 May Frontier Airlines
03 May Frontier Airlines
20 May Hawaiian Airlines
08 May Frontier Airlines
19 May Scandinavian Airlines

Also check the deals for return flights from San Francisco to Rome in May.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Rome

Cheap car rent in Rome