Cheapest one-way flights from San Francisco to Panama City in April from $208

Best time to book flights for San Francisco (SFO) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest one-way flights from San Francisco (SFO) to Panama City (PTY) in April 2025 (see full year).

One-Way flights

08 Apr Avianca
11 Apr Avianca
06 Apr Avianca
05 Apr Avianca
08 Apr Copa direct
11 Apr Copa direct
06 Apr Copa direct
05 Apr Copa direct

Also check the deals for return flights from San Francisco to Panama City in April.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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