Cheapest one-way flights from Southampton to Milano in September from $158

Best time to book flights for Southampton (SOU) to Milano (MXP) flights at AirHint

AirHint found the following cheapest one-way flights from Southampton (SOU) to Milano (MXP) in September 2025 (see full year).

One-Way flights

20 Sep easyJet

Also check the deals for return flights from Southampton to Milano in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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