Cheapest one-way flights from Quito to Santiago in April from $225

Best time to book flights for Quito (UIO) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest one-way flights from Quito (UIO) to Santiago (SCL) in April 2025 (see full year).

One-Way flights

24 Apr Copa
15 Apr Copa
16 Apr JetSmart

Also check the deals for return flights from Quito to Santiago in April.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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