Cheapest one-way flights from Santa Cruz to Madrid in September from $643

Best time to book flights for Santa Cruz (VVI) to Madrid (MAD) flights at AirHint

AirHint found the following cheapest one-way flights from Santa Cruz (VVI) to Madrid (MAD) in September 2025 (see full year).

One-Way flights

23 Sep Avianca
19 Sep Avianca
02 Sep Boliviana de Aviacion
15 Sep GOL Linhas Aéreas
12 Sep Avianca
11 Sep Avianca
01 Sep GOL Linhas Aéreas
06 Sep Avianca
15 Sep Boliviana de Aviacion direct
02 Sep Boliviana de Aviacion direct

Also check the deals for return flights from Santa Cruz to Madrid in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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