Cheapest one-way flights from Santa Cruz to Panama City in April from $230

Best time to book flights for Santa Cruz (VVI) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest one-way flights from Santa Cruz (VVI) to Panama City (PTY) in April 2025 (see full year).

One-Way flights

07 Apr Avianca
19 Apr Avianca
20 Apr Avianca
07 Apr Copa direct
19 Apr Copa direct
20 Apr Copa direct

Also check the deals for return flights from Santa Cruz to Panama City in April.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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