AirHint found the following cheapest return flights from Boston (BOS) to Prague (PRG) in October 2025 (see full year).

Return flights

21 Oct - 04 Nov	SWISS
28 Oct - 11 Nov	SWISS
22 Oct - 04 Nov	Air Canada
29 Oct - 11 Nov	SWISS
29 Oct - 12 Nov	SWISS
14 Oct - 04 Nov	Air Canada
08 Oct - 04 Nov	Air Canada
21 Oct - 12 Nov	SWISS
22 Oct - 11 Nov	Air Canada
21 Oct - 11 Nov	SWISS
08 Oct - 29 Oct	SWISS
14 Oct - 29 Oct	Scandinavian Airlines
14 Oct - 28 Oct	Scandinavian Airlines
01 Oct - 15 Oct	Icelandair
14 Oct - 24 Oct	Icelandair
01 Oct - 22 Oct	Icelandair
04 Oct - 18 Oct	Scandinavian Airlines
15 Oct - 28 Oct	Air Canada
07 Oct - 28 Oct	Air Canada
15 Oct - 29 Oct	Aer Lingus

Also check the deals for one-way flights from Boston to Prague in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Boston to Prague in October from $362

Return flights