Cheapest return flights from Rome to Istanbul in September from $193

Best time to book flights for Rome (CIA) to Istanbul (IST) flights at AirHint

AirHint found the following cheapest return flights from Rome (CIA) to Istanbul (IST) in September 2025 (see full year).

Return flights

09 Sep - 16 Sep Ryanair
10 Sep - 10 Oct Ryanair
24 Sep - 28 Sep Ryanair
02 Sep - 09 Sep Ryanair
05 Sep - 14 Sep Ryanair
12 Sep - 19 Sep Ryanair
01 Sep - 13 Sep Ryanair
22 Sep - 28 Sep Ryanair
06 Sep - 10 Sep Ryanair
02 Sep - 10 Sep Ryanair
04 Sep - 07 Sep Ryanair

Also check the deals for one-way flights from Rome to Istanbul in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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