Cheapest return flights from Rome to Madrid in September from £123

Best time to book flights for Rome (CIA) to Madrid (MAD) flights at AirHint

AirHint found the following cheapest return flights from Rome (CIA) to Madrid (MAD) in September 2025 (see full year).

Return flights

19 Sep - 23 Sep Ryanair
01 Sep - 10 Sep Ryanair
01 Sep - 03 Sep Ryanair
11 Sep - 01 Oct Ryanair
01 Sep - 20 Sep Ryanair
22 Sep - 02 Oct Ryanair
25 Sep - 02 Oct Ryanair
11 Sep - 16 Sep Ryanair
12 Sep - 16 Sep Ryanair
16 Sep - 04 Oct Ryanair
08 Sep - 11 Sep Ryanair
02 Sep - 05 Sep Ryanair
01 Sep - 04 Sep Ryanair
04 Sep - 11 Sep Ryanair

Also check the deals for one-way flights from Rome to Madrid in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Madrid

Cheap car rent in Madrid