Cheapest return flights from Denver to Panama City in December from $684

Best time to book flights for Denver (DEN) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest return flights from Denver (DEN) to Panama City (PTY) in December 2025 (see full year).

Return flights

01 Dec - 15 Dec American Airlines
01 Dec - 15 Dec Copa direct
18 Dec - 30 Dec Delta
19 Dec - 31 Dec Copa direct

Also check the deals for one-way flights from Denver to Panama City in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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