AirHint found the following cheapest return flights from Des Moines (DSM) to Istanbul (IST) in December 2025 (see full year).
Return flights
| 07 Dec - 14 Dec | Lufthansa | ||
| 06 Dec - 13 Dec | Allegiant Air | ||
| 08 Dec - 15 Dec | Allegiant Air | ||
| 20 Dec - 17 Jan | Allegiant Air | ||
| 19 Dec - 11 Jan | Allegiant Air |
Also check the deals for one-way flights from Des Moines to Istanbul in December.
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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.
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