Cheapest return flights from Frankfurt to Panama City in December from $660

Best time to book flights for Frankfurt (FRA) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest return flights from Frankfurt (FRA) to Panama City (PTY) in December 2025 (see full year).

Return flights

01 Dec - 14 Dec United
01 Dec - 06 Dec United
06 Dec - 27 Dec United
04 Dec - 12 Dec United
27 Dec - 16 Jan United
29 Dec - 12 Jan Turkish Airlines
27 Dec - 09 Jan United
26 Dec - 10 Jan Turkish Airlines
27 Dec - 10 Jan Turkish Airlines
25 Dec - 12 Jan Turkish Airlines
25 Dec - 10 Jan Turkish Airlines
22 Dec - 12 Jan Turkish Airlines
24 Dec - 11 Jan Turkish Airlines
19 Dec - 10 Jan Turkish Airlines
23 Dec - 30 Dec United

Also check the deals for one-way flights from Frankfurt to Panama City in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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