Cheapest return flights from Frankfurt to Panama City in September from $645

Best time to book flights for Frankfurt (FRA) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest return flights from Frankfurt (FRA) to Panama City (PTY) in September 2025 (see full year).

Return flights

02 Sep - 18 Sep KLM
21 Sep - 28 Sep Air France
13 Sep - 20 Sep KLM
15 Sep - 28 Sep KLM
01 Sep - 30 Sep KLM
04 Sep - 18 Sep KLM
18 Sep - 22 Sep KLM
21 Sep - 25 Sep Air France
10 Sep - 18 Sep KLM
09 Sep - 07 Oct KLM
28 Sep - 09 Oct Air France
03 Sep - 18 Sep Air France
28 Sep - 09 Oct Condor direct
29 Sep - 16 Oct Air France
29 Sep - 10 Oct Air France

Also check the deals for one-way flights from Frankfurt to Panama City in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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