Cheapest return flights from Istanbul to Rome in September from $167

Best time to book flights for Istanbul (IST) to Rome (FCO) flights at AirHint

AirHint found the following cheapest return flights from Istanbul (IST) to Rome (FCO) in September 2025 (see full year).

Return flights

24 Sep - 01 Oct Wizz Air UK
02 Sep - 09 Sep Pegasus Airlines
26 Sep - 30 Sep Pegasus Airlines
20 Sep - 24 Sep Pegasus Airlines
19 Sep - 03 Oct Air Serbia
17 Sep - 24 Sep Air Serbia
19 Sep - 23 Sep Air Serbia
22 Sep - 30 Sep Air Serbia
16 Sep - 28 Sep Air Serbia
15 Sep - 22 Sep Wizz Air
17 Sep - 23 Sep Pegasus Airlines
13 Sep - 17 Sep Pegasus Airlines
29 Sep - 04 Oct Air Serbia
24 Sep - 01 Oct AJet direct
27 Sep - 04 Oct Pegasus Airlines
27 Sep - 04 Oct AJet direct
29 Sep - 04 Oct AJet direct
30 Sep - 19 Oct Vueling Airlines
19 Sep - 03 Oct ITA Airways direct
29 Sep - 19 Oct Vueling Airlines

Also check the deals for one-way flights from Istanbul to Rome in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Rome

Cheap car rent in Rome