Cheapest return flights from Istanbul to Madrid in December from $196
AirHint found the following cheapest return flights from Istanbul (IST) to Madrid (MAD) in December 2025 (see full year).
Return flights
| 05 Dec - 07 Dec | Wizz Air UK | ||
| 22 Dec - 05 Jan | KLM | ||
| 22 Dec - 04 Jan | KLM | ||
| 05 Dec - 07 Dec | Air Europa | direct | |
| 22 Dec - 05 Jan | Turkish Airlines | direct | |
| 22 Dec - 04 Jan | Turkish Airlines | direct |
Also check the deals for one-way flights from Istanbul to Madrid in December.
The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.
