Cheapest return flights from Madrid to Guayaquil in September from $873

Best time to book flights for Madrid (MAD) to Guayaquil (GYE) flights at AirHint

AirHint found the following cheapest return flights from Madrid (MAD) to Guayaquil (GYE) in September 2025 (see full year).

Return flights

12 Sep - 08 Oct LATAM Airlines Group
17 Sep - 28 Sep Avianca
29 Sep - 21 Oct LATAM Airlines Group
08 Sep - 21 Sep LATAM Airlines Group
10 Sep - 24 Sep LATAM Airlines Group
03 Sep - 19 Sep LATAM Airlines Group
08 Sep - 29 Sep LATAM Airlines Group
24 Sep - 10 Oct LATAM Airlines Group
12 Sep - 08 Oct Air Europa direct
24 Sep - 10 Oct Air Europa direct
21 Sep - 01 Oct Air Europa direct
18 Sep - 28 Sep Avianca
23 Sep - 18 Oct Avianca
21 Sep - 28 Sep Avianca
19 Sep - 30 Sep Avianca
21 Sep - 28 Sep Air Europa direct
17 Sep - 28 Sep Air Europa direct

Also check the deals for one-way flights from Madrid to Guayaquil in September.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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