Cheapest return flights from Madrid to Istanbul in April from $173

Best time to book flights for Madrid (MAD) to Istanbul (IST) flights at AirHint

AirHint found the following cheapest return flights from Madrid (MAD) to Istanbul (IST) in April 2025 (see full year).

Return flights

09 Apr - 13 Apr Wizz Air Malta
01 Apr - 08 Apr Wizz Air
01 Apr - 07 Apr Wizz Air
10 Apr - 13 Apr Wizz Air Malta
03 Apr - 10 Apr Wizz Air Malta
02 Apr - 09 Apr Wizz Air Malta
02 Apr - 08 Apr Wizz Air Malta
05 Apr - 07 Apr Wizz Air Malta
09 Apr - 12 Apr Wizz Air Malta
24 Apr - 29 Apr Iberia
24 Apr - 08 May Iberia
27 Apr - 05 May Iberia Express
28 Apr - 05 May Iberia
28 Apr - 04 May Iberia
26 Apr - 04 May easyJet
27 Apr - 04 May Iberia
29 Apr - 05 May Air Europa
29 Apr - 04 May Air Europa
27 Apr - 10 May Iberia
25 Apr - 02 May Air Europa

Also check the deals for one-way flights from Madrid to Istanbul in April.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Istanbul

Cheap car rent in Istanbul