Cheapest return flights from Madrid to Panama City in November from $662

Best time to book flights for Madrid (MAD) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest return flights from Madrid (MAD) to Panama City (PTY) in November 2025 (see full year).

Return flights

22 Nov - 30 Nov KLM
18 Nov - 30 Nov KLM
14 Nov - 21 Nov Air Europa direct
14 Nov - 30 Nov Air Europa direct
22 Nov - 30 Nov Air Europa direct
17 Nov - 30 Nov KLM
04 Nov - 18 Nov Air Europa direct
04 Nov - 11 Nov Air Europa direct
01 Nov - 15 Nov Air Europa direct
05 Nov - 25 Nov Air Europa direct
22 Nov - 13 Dec Air France
01 Nov - 11 Dec Air France

Also check the deals for one-way flights from Madrid to Panama City in November.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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