Cheapest return flights from Madrid to Panama City in November from $664

Best time to book flights for Madrid (MAD) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest return flights from Madrid (MAD) to Panama City (PTY) in November 2025 (see full year).

Return flights

05 Nov - 12 Nov Air Europa direct
03 Nov - 15 Nov Air Europa direct
17 Nov - 24 Nov Air Europa direct
01 Nov - 15 Nov Air Europa direct
01 Nov - 16 Nov Air Europa direct
17 Nov - 01 Dec Air Europa direct
07 Nov - 16 Nov Air Europa direct
08 Nov - 16 Nov Air Europa direct
30 Nov - 27 Dec Air Europa direct
18 Nov - 29 Nov Air France
04 Nov - 14 Nov KLM

Also check the deals for one-way flights from Madrid to Panama City in November.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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